Evaluation of Ginkgo Biloba Extract on Hematological Changes Affected with Hazards of Electromagnetic Field Exposure

摘要

The aim of the present work is to study if the GBE 761 (Ginkgo biloba leaves extract) which is beneficialin arterial disease owing to its vasodilator and blood flow acts against the hazards of exposure to electro-magnetic field. Here, the GBE was used in two ways either as a protector or for treating the hazards due toexposure to electromagnetic field (EMF). For this purpose, albino rats were grouped into six groups andblood samples were collected from eye vein of the animals from all groups at the end of the experiment. Thisstudy concentrates on the cellular membrane and function of the RBCs and focuses on the rheological andphysical measurements for blood and hemoglobin molecule because the RBCs membranes play an essen-tial role in the blood flow rate. The changes in its biophysical properties of RBCs membrane will affect itscapability for carrying on its metabolic functions. Furthermore, the molecular diameter of hemoglobin, itsrelaxation time and conductivity were calculated from the dielectric relaxation data. The results indicatethat the administration of GBE led to the decrease of RBCs membrane elasticity will lead to the increase ofthe blood viscosity. Results suggest that GBE may be not of clinical value as anti-oxidant drug for such dis-eases occurred due to to EMF exposure for long time. It may be conclude that through treatment with thoseextract some physical measurements like "viscosity of blood, Osmotic fragility to measure the hemolysis ratof RBCs, the radius and the conductivity of hemoglobin molecule" should be considered during the time oftreatment. Overall, these leaves (GBE) need more study and there is a recommendation to put the physicalparameters parallel to the clinical study. (Int J Biomed Sci 2009; 5(3):229-236)