Studies towards the Synthesis of Aldgamycin - M

摘要

abstract_textpA convergent and highly stereoselctive synthesis of macrolide framework of aldgamycin - M is described. The salient features of the synthesis are the utilization of enzymatic desymmetrization, Crimmin's non-Evans syn aldol reaction, Wittig olefination, Yamaguchi esterification and Ring closing metathesis reaction (RCM)./p/abstract_text