Electrochemically generated base synthesis of thiazolidine-2-thiones

摘要

The electrolysis of secondary -amino alcohols in the presence of carbon disulfide using an electrogenerated base (EGB) to promote the reaction of the synthesis of thiazolidine-2-thione is reported. The EGB was prepared by probase-free electrolysis of acetonitrile under galvanostatic conditions using a sacrificial magnesium anode. The reaction produces the corresponding heterocyclic thiazolidine-2-thiones in satisfactory yields. The compounds thus obtained were fully characterized by IR, H-1, C-13 NMR spectroscopy, HRMS and elementary analysis.