Aerobic Oxidation of Methyl-substituted beta-Carbolines Catalyzed by N-Hydroxyphthalimide and Metal Catalyst

摘要

abstract_textpCarboxylic functionalized beta-carbolines were successfully synthesized in good to excellent yields and high selectivity under mild conditions by aerobic oxidation in the presence of NHPI and transition metal salt using molecular oxygen as an oxidizing agent. A variety of derivatives of fascaplysin thus are available for structure-bioactivity investigations./p/abstract_text