α-hydroaxyalkyl(benzyl)furozans and α-hydroxyalkyl(benzyl)furoxans synthesis and reactivity

摘要

A general and simple preparative method for the synthesis of α-hydroxyalky(benzyl)furazan and -furoxan derivatives is proposed, The method involves reduction of acyl or ethoxycarbonyl substituents in these heterocyclic compounds with NaBH4in ethanol. Based on the alcohols thus prepared, a number of previously unknown functional derivatives (α-nitroxyalkyl-α-haloalkyl-, and α-azidoalkylfurazans and -furoxans) have been synthesi