AIMS: To evaluate the effect of acute elevation of intraocular pressure (IOP) on optic disc cupping. METHODS: 10 emmetropic and 10 myopic volunteers were included in this study. The cup area (CA) and cup volume (CV) of the optic disc were determined with the Heidelberg retina tomograph (HRT). After baseline determinations, a suction cup was used to increase the intraocular pressure (IOP) to 20-25 mm Hg above the baseline and HRT images were obtained. RESULTS: Baseline IOP was 13.5 (SD 1.3) nim Hg and 12.6 (2.6) mm Hg in the emmetropic and myopic groups, respectively. The IOP was elevated to 35.4 (3.3) mm Hg and 34.4 (2.5) mm Hg in the emmetropic and myopic groups, respectively. When compared with their baseline values, the cupping variables (CA and CV) were significantly increased (p < 0.05) during the suction treatment in both emmetropic and myopic subjects. CONCLUSION: There was a significant enlargement in the optic disc cupping during the artificial increment of intraocular pressure in both emmetropic and myopic eyes. In non-glaucomatous eyes the optic nerve head has a partially dynamic topography dependent upon the level of IOP.
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机译：目的：评估眼内压（IOP）急性升高对视盘拔罐的影响。方法：本研究包括10名正视眼和10名近视眼志愿者。用海德堡视网膜断层扫描仪（HRT）确定视盘的杯面积（CA）和杯体积（CV）。在确定基线之后，使用吸盘将眼内压（IOP）增加到基线之上20-25 mm Hg，并获得HRT图像。结果：正视和近视组的基线眼压分别为13.5（SD 1.3）mm Hg和12.6（2.6）mm Hg。在正视眼组和近视眼组中，眼压分别升高到35.4（3.3）mm Hg和34.4（2.5）mm Hg。当与基线值比较时，在正视眼和近视眼受试者的抽吸治疗期间，拔罐变量（CA和CV）显着增加（p <0.05）。结论：在正视眼和近视眼人工增高眼压期间，视盘拔罐明显增大。在非青光眼中，视神经乳头的局部地形取决于IOP的水平。
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