Explanation of anomalous mobility and birefringence measurements found in pulsed field electrophoresis

摘要

The study of DNA in a gel under the application of a timehyphen;dependent field has revealed some unexpected experimental features. These features are recovered by means of a detailed numerical simulation incorporating the many internal degrees of freedom of the DNA chain. These results can in turn be understood qualitatively by means of a model containing only four degrees of freedom.