Notiz zur Darstellung vonN-substituierten Aminoglycerinaldehyden

摘要

O-Benzyl-N-(benzyloxycarbonyl)-DL-serine methyl ester (1a) and peptides1 b–dwith C-terminalO-benzylserine ester have been reduced with diisobutylaluminium hydride to yield the N-substituted aminoglyceraldehydes2 a–d. Using lithium tetrahydridoaluminate as the reducing agent the corresponding alcohols3 a–dhave been obt