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Associate Editor David Dombrowicz

机译:副编辑大卫·唐布罗维兹

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David Dombrowicz was trained as a biologist and as botanist and obtained his PhD in endocrinology in 1991 from the University of Liege (Belgium). During his post-doctoral fellowship at NIH/NIAID (Bethesda, Md., USA) in the laboratory of Dr. Jean-Pierre Kinet, he performed the first inactivation of the a and (3 subunits of the high-affinity IgE receptor FceRI and studied the role of this receptor as well as FcyRIII/CD16 in anaphylactic reactions. In 1996, he joined the INSERM Unit led by Prof. Andre Capron (at the Institut Pasteur de Lille, France). Together with Prof. Monique Capron he further investigated the role of Fc receptors, in particular their expression and function on eosinophils and in allergic and inflammatory diseases (asthma, atopic dermatitis and colitis). In 1999, he received the award from the Pharmacia Allergy Research Foundation. He later studied the immunoregulatory properties of prostaglandin D2 and nuclear receptors, in particular peroxisome pro-liferator-activated receptors. Since 2005, he has been Research Director at INSERM. In 2010, he joined the INSERM Unit led by Bart Staels (Institut Pasteur de Lille) to lead a team working on nuclear receptors and immuno-metabolism.
机译:David Dombrowicz受过生物学家和植物学家的培训,并于1991年从列日大学(比利时)获得内分泌学博士学位。在让·皮埃尔·基内特(Jean-Pierre Kinet)实验室在美国国立卫生研究院(NIH / NIAID)(美国马里兰州贝塞斯达)进行博士后研究期间,他进行了a和(3个高亲和力IgE受体FceRI和研究了该受体以及FcyRIII / CD16在过敏反应中的作用,1996年,他加入了安德烈·卡普伦教授(法国里尔巴斯德研究所)领导的INSERM部门,与莫妮克·卡普伦教授一起进行了进一步的研究。 Fc受体的作用,特别是它们在嗜酸性粒细胞以及变应性和炎症性疾病(哮喘,特应性皮炎和结肠炎)中的表达和功能。1999年,他获得了Pharmacia过敏研究基金会的奖励,后来研究了Fc受体的免疫调节特性。前列腺素D2和核受体,特别是过氧化物酶体增殖物激活受体。自2005年以来,他担任INSERM的研究总监。2010年,他加入了由Bart Staels(巴斯德·里尔研究所)领导的INSERM部门)领导一个研究核受体和免疫代谢的小组。

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