Primary urethral carcinomas are rare. The diagnostic evaluation, pathological classification, and the potential use of two new markers, CA 19ndash;9 and IsA immunoglobulin, are discussed in this review. The treatment of urethral carcinoma depends on the gender of the patient, the location and the clinical stage of the tumor. The use of a combined modality approach in selected patients will be used with increasing frequency in future.
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