Restriction fragment length polymorphisms detected by anonymous DNA probes mapped to defined intervals of human chromosome 16

摘要

Three anonymous DNA probes ACH207, ACH224, and ACH202, isolated from a flow-purified chromosome 16 library and mapped to defined intervals of human chromosome 16, detected restriction fragment length polymorphisms (RFLPs). The RFLPs were of simple two allele types. The ACH207 (D16S4) probe detected aTaqI and anMspI RFLP with polymorphism information content (PIC) values of 0.30 and 0.27; the ACH224 (D16S5) probe detected andRsaI RFLP, PIC value of 0.34; and the ACH202 (D16S14) probe detected anXbaI RFLP, PIC value of 0.22.