A prospective study of the factors affecting outcomes of nonsurgical root canal treatment: part 1: periapical health.

摘要

AIM: To investigate the probability of and factors influencing periapical status of teeth following primary (1 degrees RCTx) or secondary (2 degrees RCTx) root canal treatment. METHODOLOGY: This prospective study involved annual clinical and radiographic follow-up of 1 degrees RCTx (1170 roots, 702 teeth and 534 patients) or 2 degrees RCTx (1314 roots, 750 teeth and 559 patients) carried out by Endodontic postgraduate students for 2-4 (50%) years. Pre-, intra- and postoperative data were collected prospectively on customized forms. The proportion of roots with complete periapical healing was estimated, and prognostic factors were investigated using multiple logistic regression models. Clustering effects within patients were adjusted in all models using robust standard error. RESULTS: proportion of roots with complete periapical healing after 1 degrees RCTx (83%; 95% CI: 81%, 85%) or 2 degrees RCTx (80%; 95% CI: 78%, 82%) were similar. Eleven prognostic factors were identified. The conditions that were found to improve periapical healing significantly were: the preoperative absence of a periapical lesion (P = 0.003); in presence of a periapical lesion, the smaller its size (P