Despite advances in antimicrobial therapy and intensive caresupport, Staphylococcus aureus con- tinues to cause significantmorbidity and mortality. We studied community-acquired S. aureusbacterae- mia in a population where intravenous drug abuse isextremely uncommon, prospectively reviewing all such patients (n=113)admitted to Groote Schuur Hospital from February 1986 to January1991. Overall mortality was 35/100. Factors associated with pooroutcome were: confusion n presentation, fail- ure to mount a febrileresponse, acute renal failure, adult respiratory distress syndrome,shock, endo- carditis, disseminated intravascular coagulation andplatelet count of<100×10~9/1.
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