ENTEROTOXIN FROM K_(99+) E. COLI

摘要

Twenty E. coli isolates including 12 K_(99+) E. coli strains were used for the studies of enterotoxins. These purified enterotoxins preparations were tested for the presence of heat stable (ST) and/or beat labile (LT) enterotoxins by using rabbet ligated gut loop method. Five enterotoxin preparations were found positive for LT and ST both and eight preparations demonstrated the presence of either ST or LT enterotoxins. Of these 13 enterotoxin preparations, 10 preparations were from K_(99+) E. coli strains. Histopathological studies revealed mild to marked desquamation of epithelial cells ot intestinal mucous membrane with varying amount of eatarrhal and haemorrhagic exudate.