High-dose methylprednisolone is effective in treating radiation-induced refractory haemorrhagic cystitis

摘要

Haemorrhagic cystitis (НС), characterised by the presentation of painful macroscopic haematuria and even obstructive renal failure or death, is commonly seen in patients undergoing cyclophosphamide and/or radiation therapy. Conventional management for HC includes continuous bladder irrigation, cystoscopic clot evacuation, electrocoagulation of bleeding vessels, intravesical therapy with chemicals (sodium hyaluronate, aluminum, granulocyte-macrophage colony-stimulating factor and prostaglandin), oestrogens and hyperbaric oxygen therapy. However, there is no standard treatment for HC.