Regression of lung mass associated with progression of neurological deficits.

摘要

An 83-year-old woman presented to the emergency department with increased confusion. She had recently been admitted to a nursing home because of a rapid decline in her mobility and cognition over a 2-month period. Her family claimed she had been 'misdiagnosed' with small-cell lung cancer (SCLC) 12 months ago.A definite diagnosis of SCLC had been made 1 year earlier by fine-needle aspiration biopsy of a lung mass and conservative approach to treatment was undertaken(Fig. 1a). Over a 9-month period there was no progression of symptoms. At this stage investigations by a different specialist showed no lung mass on chest computed tomography (CT), normal bronchoscopic finding and a negative cytology study. The original diagnosis of SCLC was therefore 'questioned'.