Management of metastatic phaeochromocytoma and paraganglioma: use of iodine-131-meta-iodobenzylguanidine therapy in a tertiary referral centre

摘要

Background: Phaeochromocytoma (phaeo) and paraganglioma (PGL) are rare conditions, which are malignant in up to 30. Optimal treatment is controversial, but in patients with metastatic iodine-(131)-meta-iodobenzylguanidine (I-123-MIBG) avid tumours, we offer I-131-MIBG therapy. We summarize response rates, survival and safety in a cohort of such patients treated with I-131-MIBG in our centre from 1986 to 2012.