A 59-year-old woman with inoperable breast carcinoma, and who was receiving chemotherapy, underwent Tc-99m MIBI myocardial perfusion scintigraphy for ischemic heart disease. Whole-body Tc-99m MIBI imaging was performed before the myocardial study showed bone marrow activity. Tc-99m MDP bone scan findings were well adjusted with superscan. Diffuse bone marrow activity seen with Tc-99m MIBI may be due to bone marrow expansion and increased metabolic activity. Bone marrow biopsy revealed secondary myelofibrosis.
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