ETHANOL DECREASES BASAL CYTOSOLIC-FREE CALCIUM CONCENTRATION IN CULTURED SKELETAL MUSCLE CELLS

摘要

We analysed the effect of ethanol on basal cytosolic-free calcium concentration (Ca2+1) in cultured rat myocytes. Ethanol caused a dose-dependent decrease of the resting Ca2+1). Removal of ethanol was followed by a transitory increase of Ca2+1above the basal level. In cells chronically exposed to ethanol, Ca2+1normalized to the previous level.