Factors influencing the provision of fertility counseling and impact on quality of life in adolescents and young adults with cancer

摘要

Purpose: This study investigated the impact of fertility-related discussions on Adolescent and Young Adult (AYA) cancer patients' quality of life (QoL) and the factors influencing provision of these discussions.Methods: Recruitment was conducted through population-based state cancer registries. Eligible AYAs were 15-24years at diagnosis, 3-24months postdiagnosis, with any cancer (except early stage melanoma). As part of a larger survey, AYAs were asked about their experiences of fertility-related discussions and QoL (FACT-G).Results: Of the 207 AYAs returning surveys (29 response rate) 88 reported a discussion about infertility risks, 75 reported a discussion about preservation options and 59 were offered a referral to a fertility specialist. Patients attending health services with an AYA focus were more likely than those attending other types of centers to report discussions of fertility preservation (FP) options (85 versus 67) and referrals (75 versus 49). Social well-being was positively related to discussions about preservation options and being provided fertility risk information in a sensitive, supportive manner.Conclusions: Providing a sensitive and proactive discussion about fertility-related risks may benefit AYAs' well-being. Services with an AYA focus are fulfilling their mandate of ensuring optimal fertility-related care for AYA cancer patients.