The study briefly reviews the life and work of Alfons Maria Jakob (1884-1931), a notable representative of pre-war German neuropathology. Today Jakob is mainly remembered by neurologists for the spongiform encephalopathy with progressive dementia and spasticity that he, and Kiel neuropathologist Hans Gerhard Creutzfeldt (1885-1964), described independently. However, Jakob has left additional contributions to neuroanatomy, neuropathology and neuropsychiatry in the form of original articles and valuable monographs.
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Economo-Koskinas Wing for Integrative and Evolutionary Neuroscience, Department of Educational and Social Policy, University of Macedonia, Thessaloniki, Greece. triarhou@uom.gr;