Clinical Analysis of Patients with Primary Blepharospasm: A Report of 100 Cases in China

摘要

Purpose: This study explored the clinical characteristics, diagnosis and treatments of primary blepharospasm. Methods: In this retrospective analysis, 100 patients with blepharospasm were enrolled. Data were collected from medical records and face-to-face interviews with patients and their families. Results: The age of onset was 56.4 +/- 2.7 (range, 3276 years). The duration between onset and accurate diagnosis was 38.7 +/- 36.0 months (range, 2-120 months). Dry eyes occurred in 54 of the patients. The initial diagnostic accuracy was 10. Dry eye syndrome, conjunctivitis/keratitis and myasthenia gravis caused the most confusion in the differential diagnosis. Regular botulinum toxin type A injections improved both eyelid spasms and subjective ocular symptoms in all patients. Conclusions: Regular botulinum toxin type A injections improved both eyelid spasms and subjective ocular symptoms in blepharospasm patients. The differentiation of primary blepharospasm differentiation from dry eye syndrome, conjunctivitis/keratitis and myasthenia gravis must be improved. (C) 2015 S. Karger AG, Basel