Gas Chromatographic Determination of O-Ethyl S-(N, N-Diisopropylamino) Ethyl Methylphosphonothiolate and O, O-Diisopropyl S-Benzyl Phosphorothiolate as Corresponding Phosphonofluoridate and Phosphorofluoridate

摘要

A gas chromatographic method has been reported for the determination of phosphonothiolates and phosphorothiolates as corresponding phosphonofluoridates and phosphorofluoridates after reaction with AgF. The transformation reaction procedures and the chromatographic conditions were recommended for the model compounds, O-ethyl S-(N,N-diisopropylamino)ethyl methylphosphonothiolate (MESP) and O,O-diisopropyl S-benzyl phosphorothiolate (DPSP). The results obtained have shown that the recovery is 100+4.5 for determination of MESP in the range of 1.88-8.00 #x3BC;g/ml (in benzene solution) and the relative standard deviations (RSD) are less than 2.12 for MESP and DPSP at the 3.18, 6.30 and 5.48 #x3BC;g/ml level.