Platelet count is an IPSS-independent risk factor predicting survival in refractory anaemia with ringed sideroblasts.

摘要

Recently, Bowles et al (2006) reported that a low platelet mass [i.e., mean platelet volume (MPV) x platelet count] is a marker for poor survival in myelodysplastic syndromes (MDS), and that the MPV provides independent prognostic information. In their 58-patient cohort, median survival was 5 months for platelet mass <0-6 ml/1, >82 months for platelet mass >l-2 ml/ 1, and 30 months for intermediate values. MPV is easily obtainable, so if the prognostic value of this measurement could be independently confirmed, platelet mass and MPV might prove clinically useful.