Blink reflex recovery cycle, before and after acute administration of orphenadrine chlorhydrate, was tested in Meige syndrome. Data here reported show, after the drug, a decrease of the unconditioned polysynaptic responses, without a significant modification of the blink reflex recovery curves. This fact rules out a specific effect of anticholinergic drugs on the pathological reduction of the inhibitory process, at an interneuronal level of these polysynaptic pathways, in Meige syndrome.
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