Zur Kenntnis der Reaktionsfähigkeit des unsubstituierten Thiomorpholins und alkylsubstituierter Thiomorpholine. 3. Mitt

摘要

A new synthesis of thiomorpholine by ring closure of β-chloro-β′-aminodiethylene-sulfide with potassium hydroxide is reported. Numerous reactions of thiomorpholine (1) and, especially, 2-methyl-3-ethyl-thiomorpholine (2) are described such as acylation, diacylation (3–43), reactions with sulfonic acid chlorides (44–52), isocyanates (53–61, 70–75), diisocyanates (62–66, 76–78) and isothiocyanates (67–69, 79–82), alkylation reactions (83–111) and the synthesis of thiomorpholino-dithi