Cyclic-AMP phosphodiesterase activity was found in crown-gall tumor tissue obtained from the inoculation of potato discs withAgrobacterium tumefacicnsstrain B6. Consistently more enzyme activity was found, in this tumor tissue than in the corresponding normal tissue. This difference in enzyme activity was observed when strains other than B6 were used to induce tumors, or when normal and tumor potato tissue grown in culture were examined for phosphodiesterase activity.
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