CHALLENGES IN INTEGRATING BIOSENSORS AND FIA FOR ON-LINE MONITORING AND CONTROL

摘要

Several obstacles prevent the increased use of biosensors in industrial bioprocess monitoring and control. Among these are the absence of robust and reliable biosensors with the required specificity and sensitivity for use in complex media, and the absence of adequate sampling techniques. Progress with the integration of amperometric and potentiometric biosensors into flow injection analysis (FIA) systems may provide a route to developing automated, reliable, on-line systems for bioprocess control.