The median percentages of peripheral blood immunoglobulin-positive (Ig+) lymphocytes (8, n = 46), CD8+ (12, n = 49) and CD57+ cell numbers (5, n = 37) of patients suffering from multiple sclerosis (MS) were significantly (p + cells: 13, n = 46; CD8+ cells: 17, n = 49; CD57+ cells: 9, n = 37). Comparison of calculations on decreased peripheral blood cell counts and increased brain cell counts in MS patients revealed that sequestration of blood cells into the MS brain is a possible explanation of these findings.
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