Effect of Preoperative Biologic Drugs on Complications and Function After Restorative Proctocolectomy with Primary Ileal Pouch Formation: Systematic Review and Meta-analysis

摘要

Background: Debate exists concerning the presumed risk of postoperative complications in patients with ulcerative colitis (UC) receiving preoperative infliximab (IFX). Meta-analyses are contrasting because of many confounders included into analysis. Our aim was to determine the impact of IFX on pouch-related postoperative complications in patients with UC undergoing surgery with primary ileal pouch-anal anastomosis.