Noncoding Transcribed Ultraconserved Region (T-UCR) uc.261 Participates in Intestinal Mucosa Barrier Damage in Crohn's Disease

Qian Xiao Xian; Peng Jiang Chen; Xu An Tao; Zhao Di; Qiao Yu Qi; Wang Tian Rong; Shen Jun; Ran Zhi Hua

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Noncoding Transcribed Ultraconserved Region (T-UCR) uc.261 Participates in Intestinal Mucosa Barrier Damage in Crohn's Disease

机译：非编码转录超保守区（T-UCR）uc.261参与克罗恩病的肠粘膜屏障损伤

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Background: To date, 481 ultraconserved regions (UCRs) have been discovered in human genome. We aimed to investigate the transcribed UCR (T-UCR) characteristics in Crohn's disease (CD) and determine whether T-UCR uc. 261 participated in intestinal mucosa barrier damage.

机译：背景：迄今为止，在人类基因组中发现了481个超保守区（UCR）。我们旨在研究克罗恩病（CD）中转录的UCR（T-UCR）特征，并确定T-UCR是否为uc。 261人参与了肠粘膜屏障的破坏。

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《Inflammatory bowel diseases》 |2016年第12期|共13页
作者
Qian Xiao Xian; Peng Jiang Chen; Xu An Tao; Zhao Di; Qiao Yu Qi; Wang Tian Rong; Shen Jun; Ran Zhi Hua;
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正文语种 eng
中图分类消化系及腹部疾病;
关键词
Crohn's disease; T-UCR; uc.261; tight junction; Cdc42; PKC zeta;

机译：克罗恩病;T-UCR;uc.261;紧密连接;Cdc42;PKC zeta;

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1. Noncoding Transcribed Ultraconserved Region (T-UCR) uc.261 Participates in Intestinal Mucosa Barrier Damage in Crohn's Disease [J] . Qian Xiao Xian, Peng Jiang Chen, Xu An Tao, Inflammatory bowel diseases . 2016,第12期

机译：非编码转录超保守区（T-UCR）uc.261参与克罗恩病的肠粘膜屏障损伤
2. The role of a new class of long noncoding RNAs transcribed from ultraconserved regions in cancer [J] . Daniela Terracciano, Sara Terreri, Filomena de Nigris, Biochimica et biophysica acta. Reviews on cancer . 2017,第2期

机译：新一类长的非分量RNA的作用从癌症中超法区域转录
3. The role of a new class of long noncoding RNAs transcribed from ultraconserved regions in cancer [J] . Daniela Terracciano, Sara Terreri, Filomena de Nigris, Biochimica et biophysica acta. Reviews on cancer . 2017,第2期

机译：一类新一类长的非分量RNA在癌症中超法区转录的作用
4. State-of-the-Art Lecture: Distinct antibacterial-defensin deficiencies in small intestinal and colonic Crohn's disease [C] . J. WEHKAMP, E.-F. STANG Falk Symposium . 2007

机译：最先进的讲义：小肠和结肠克罗恩病中不同的抗菌 - 防御素缺乏
5. Defective Epithelial Barrier Function in Chronic Inflammation of the Intestinal Mucosa =Defekte Epitheliale Barrierefunktion bei Chronischer Entzündung der Darmschleimhaut [D] . Delbue da Silva, Deborah. 2021

机译：肠粘膜慢性炎症中的上皮屏障功能有缺陷的上皮阻隔功能=肠粘膜慢性炎症中的缺陷上皮阻挡功能
6. Transcribed ultraconserved region (T-UCR) uc.261 expression isclosely correlated with disease activity and intestinal permeability in Crohn’sdisease [O] . Xiao-Xian Qian, Chen-Wen Cai, Han-Yang Li, 2019

机译：转录的超保守区（T-UCR）uc.261表达为与克罗恩病的疾病活动性和肠道通透性密切相关疾病
7. Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis. [O] . Fassan M, DallOlmo L, Galasso M, 2014

机译：转录的超保守非编码RNa（T-UCR）参与Barrett食管癌的发生。

Noncoding Transcribed Ultraconserved Region (T-UCR) uc.261 Participates in Intestinal Mucosa Barrier Damage in Crohn's Disease

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