Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis

Long Rui; Zhou Yuanda; Huang Jiangju; Peng Li; Meng Long; Zhu Shenyin; Li Juan

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Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis

机译：苄基溴化喹在过敏性鼻炎大鼠模型中抑制鼻分泌过多

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摘要

This study is aimed at exploring the effect of Bencycloquidium bromide (BCQB), a novel M1/M3 receptor antagonist, on mucus secretion in a murine model of allergic rhinitis (AR).

机译：这项研究的目的是探索一种新型的M1 / M3受体拮抗剂溴化苄基喹啉（BCQB）对变应性鼻炎（AR）鼠模型中的粘液分泌的影响。

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《Inflammation research: Official journal of the European Histamine Research Society 》 |2015年第4期| 共11页
作者
Long Rui; Zhou Yuanda; Huang Jiangju; Peng Li; Meng Long; Zhu Shenyin; Li Juan;
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正文语种 eng
中图分类病理学 ;
关键词
Bencycloquidium bromide; Allergic rhinitis; Hypersecretion; Mucin 5AC; NF-kappa B;

机译：溴环十二烷;过敏性鼻炎;高分泌;Mucin 5AC;NF-κB;

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专利

1. Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis [J] . Long Rui, Zhou Yuanda, Huang Jiangju, Inflammation research: Official journal of the European Histamine Research Society . 2015 ,第3a4期

机译：苄基溴化喹在过敏性鼻炎大鼠模型中抑制鼻分泌过多
2. Mast cell inhibitor R112 is well tolerated and affects prostaglandin D2 but not other mediators, symptoms, or nasal volumes in a nasal challenge model of allergic rhinitis. [J] . Guyer BJ, Shimamoto SR, Bradhurst AL, Allergy and asthma proceedings . 2006 ,第3期

机译：肥大细胞抑制剂R112具有良好的耐受性，并且在变应性鼻炎的鼻攻击模型中影响前列腺素D2，但不影响其他介质，症状或鼻腔容积。
3. Desloratadine citrate disodium injection, a potent histamine H-1 receptor antagonist, inhibits chemokine production in ovalbumin-induced allergic rhinitis guinea pig model and histamine-induced human nasal epithelial cells via inhibiting the ERK1/2 and NF-kappa B signal cascades [J] . Chen Meiling, Xu Shuhong, Zhou Peipei, European Journal of Pharmacology: An International Journal . 2015 ,第Null期

机译：柠檬酸去氯雷他定二钠注射液，一种有效的组胺H-1受体拮抗剂，通过抑制ERK1 / 2和NF-κB信号级联反应，抑制卵清蛋白诱导的过敏性鼻炎豚鼠模型和组胺诱导的人鼻上皮细胞的趋化因子生成。
4. Shubiling Nasal Spray effects on allergic rhinitis models of rats [C] . Mingsan Miao, Zhenzhen Wei, Baoxin Yang International Forum on Materials Analysis and Testing Technology . 2014

机译：蜂鸣鼻喷雾对大鼠过敏性鼻炎模型的影响
5. The impact of nasal congestion and rural residence on pulmonary function and asthma control in adults with asthma and allergic rhinitis. [D] . Hogan, Donna Grace. 2011

机译：鼻充血和农村居民对哮喘和过敏性鼻炎成人的肺功能和哮喘控制的影响。
6. Luteolin Attenuates Allergic Nasal Inflammation via Inhibition of Interleukin-4 in an Allergic Rhinitis Mouse Model and Peripheral Blood From Human Subjects With Allergic Rhinitis [O] . Kai-Li Liang, Sheng-Jie Yu, Wan-Chun Huang, 2020

机译：木犀草素通过抑制过敏性鼻炎小鼠模型和人类过敏性鼻炎患者的外周血白细胞介素4抑制过敏性鼻炎症
7. Relationship between Density of Muscarinic Receptors and Nasal Hypersecretion in a Nasal Allergic Model [O] . Akio Namimatsu, Ryohei Okazaki, Koichiro Go, 1992

机译：鼻过敏模型中毒蕈碱受体密度与鼻腔折叠的关系

Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis

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