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首页> 外文期刊>Inflammation research: Official journal of the European Histamine Research Society >4. Synthesis, metabolism and release of histamine Characterization of human plasma amine oxidase
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4. Synthesis, metabolism and release of histamine Characterization of human plasma amine oxidase

机译:4.组胺的合成,代谢和释放人血浆胺氧化酶的特征

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摘要

Recently the amine oxidase present in human blood plasma has triggered considerable interest when it was found that its activity was significantly increased in various diseases including diabetes, liver inflammation and obesity and by circumstantial evidence that this increased activity may lead to vascular complications in these patients . The apparent lack of information on this enzyme prompted us to purify human plasma amine oxidase (PAO) and study its molecular and enzymatic properties.
机译:最近,当发现血浆中的胺氧化酶活性在包括糖尿病,肝炎和肥胖症在内的多种疾病中显着增加时,已经引起了人们的极大兴趣,并且有间接证据表明这种活性增加可能导致这些患者的血管并发症。关于此酶的信息明显不足,促使我们纯化人血浆胺氧化酶(PAO)并研究其分子和酶学性质。

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