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A feasible method for measuring the blood flow velocity in superficial artery based on the laser induced dynamic thermography

机译:基于激光动态热成像技术的一种可行的测量浅动脉血流速度的方法

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摘要

Infrared thermography has been proved to be a useful tool to detect thermal physiologic changes associated with various diseases. However, static and single point temperature mapping on skin surface provided by the infrared thermography has not been able to meet the requirements for evaluating the complicated physiological status of human body. In order to explore more physiological variables for possible disease diagnostics, the present paper has developed a laser induced dynamic thermographic modality to estimate the average velocity of the superficial blood flow by means of tracking thermal transport along blood flow direction. A conceptual in vivo experiment is designed to record dynamic temperature response of rabbit auricle skin by thermograph, which is then used to estimate the blood flow velocity through a derived theoretical model. In addition, the lumped parameter model is developed to calibrate the estimated error by compensating the thermal response time induced by the tissue temperature change that the current infrared thermal imaging system with limited thermal sensitivity may fail to capture. The final calibrated results are fitting well with that from the Doppler ultrasound measurement, which indeed verified the practicality and feasibility of the method developed in this work.
机译:红外热成像已被证明是检测与各种疾病相关的热生理变化的有用工具。然而,由红外热成像技术在皮肤表面上进行的静态和单点温度映射无法满足评估人体复杂生理状态的要求。为了探索更多的生理变量以进行可能的疾病诊断,本论文开发了一种激光诱导的动态热成像方式,以通过跟踪沿血流方向的热传输来估算浅层血流的平均速度。设计了一个概念性的体内实验,通过热像仪记录兔子耳廓皮肤的动态温度响应,然后将其用于通过导出的理论模型估算血流速度。另外,集总参数模型被开发来通过补偿由组织温度变化引起的热响应时间来校准估计的误差,该热响应时间是当前具有有限热灵敏度的红外热成像系统可能无法捕获的。最终的校准结果与多普勒超声测量的结果非常吻合,这确实证明了这项工作中开发的方法的实用性和可行性。

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