Fatal Disseminated Mycobacterium marinum Infection With Bacteremia in a Patient Misdiagnosed as Pyoderma Gangrenosum

摘要

Mcobacterium marinum is an "atypical" mycobacte-rium also known as a mycobacterium other than tuberculosis belonging to the Runyon group I, the photo-chromogens. Colonies form a yellow pigment upon exposure to light, and optimal growth of the organism occurs at 30 to 32°C. First described in 1926 when Aronson isolated it from saltwater fish that had died in the Philadelphia aquarium, M. marinum is now a well-known cause of cutaneous infection in humans, usually occurring because of minor trauma in association with fresh, salt, or brackish water. Most commonly, the infection produces localized cutaneous lesions, but sporotrichoid spread along lymphatics may occur and infection can extend to deeper structures. Cutaneous dissemination has been reported rarely, and systemic dissemination with involvement of deep-seated tissues and organs is extremely rare, most cases being associated with immunocompromising conditions.