Influence of interleukin 10 polymorphisms-592 and-1082 to the HIV, HBV and HCV serostatus among intravenous drug users

摘要

Background: Interleukin 10 (IL-10) is a multifunctional cytokine produced by macrophages, monocytes, and T-helper cells. Two polymorphisms at positions -592 and -1082 have been associated with HIV susceptibility. However, their associations with susceptibility to HIV and its co-infections among intravenous drug users (IDUs) are largely unknown.