Risk factor for death in hematopoietic stem cell transplantation: are biomarkers useful to foresee the prognosis in this population of patients?

摘要

Out of the biomarkers assessed, only CRP ≥120?mg/L was independently associated with death. Other risk factors found were: type of transplantation (allogeneic and unrelated), bloodstream infection by Gram-negative, LDH ≥390?UI/L and urea ≥25?mg/dL. For allogeneic patients only CRP ≥120?mg/L and BSI due to Gram-negative were risk factors for death; however, CRP did not remain in the model when urea ≥25?mg/L was included.