Luminescence enhancement effect for the determination of balofloxacin with balofloxacin-europium (III)-sodium dodecylbenzene sulfonate system

摘要

A novel method of luminescence enhancement effect for the determination of balofloxacin (BLFX) was proposed. A new system of the BLFX-Eu3+-SDBS (sodium dodecylbenzene sulfonate) was investigated. It was found that SDBS significantly enhanced the luminescence intensity of the BLFX-Eu3+ complex (about 20-fold). Under the optimized experimental conditions, the system exhibits an excellent linear relationship between the enhanced luminescence intensity and the concentration of BLFX over the range of 1.0 x 10(-8)-8.0 x 10(-7) mol L-1 with a correlation coefficient (R) of 0.9994. and the detection limit (3 sigma) of the method was determined as 2.0 x 10(-9) mol L-1. This method has been successfully applied for the determination of BLFX in pharmaceuticals and human urine/serum samples. Compared with most of the other methods reported, the rapid and simple procedure proposed in the text offers higher sensitivity, wider linear range, and better stability. (C) 2008 Elsevier B.V. All rights reserved.