An attempt has been made to show that as well as the very well-known mediators such as angiotensin, catecholamines, and prostaglandins, other substances are important either pathophysiologically or even as physiological regulators of renal blood flow. From this last point of view the vasoconstrictors leukotrienes, adenosine, and neuropeptide Y, and the vasodilators adenosine and histamine seem to fulfil this role.
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