An Automated Protein Crystallization and Imaging Workstation for Hanging Drop and Sitting Drop Crystallization

摘要

Pharmaceutical drug discovery is increasingly focusing attention on structural genomics to improve target identification, rational drug design, and basic proleomic research. Large-scale structural genomics requires automated, parallel crystallizationprocedures to optimize crystal growth. This paper describes a protein crystallization workstation developed for hanging drop and sitting drop crystallization methods.