A review of high-throughput screening approaches for drug discovery

摘要

The HTS field continues to be dynamic and very competitive. However, there is also a good deal of information sharing, even between competing companies. The somewhat open technology transfer meetings and publications have greatly accelerated the development of the industry. It is an industry that has been significantly driven by implementing technologies from vendor companies rather than through developments occurring within drug research companies. The future will certainly hold change as the industry strives to reach such high-density formats as the 1536-well plate, and such technologies as microassay systems using nanoscale capillaries. However, for the moment, these technologies are still a few years away from routine in-house screening.