Rapid High-Performance Liquid Chromatographic Determination of Physostigmine in Plasma

摘要

A new method is described for the quantitative determination of physostigmine in human plasma. The drug is isolated from human plasma utilizing a C18SEP PAK Cartridge, and quantified by liquid chromatography with ultraviolet detection. The average recovery is 54.3 #xB1; 4.3 (S.D.) with a day to day coefficient of variation of 4.