Studies on healing of sutured and unsutured prescrotal urethrotomy wounds in dogs

摘要

In dogs urethrotomy is a routine procedure performed to remove urethral calculi. Some surgeons allow the urethral incision to heal by second intention to avoid complication of urethral stricture (Brown, 1975), while others recommend primary closure ofincision to promote early healing (Mohindra et al., 1996). In the present study healing of sutured and unsutured prescrotal urethrotomy wounds were evaluated in dogs. In overnight fasted 12 healthy adult mongrel dogs, prescrotal urethrotomy was performed (Weber et al., 1985) under atropine-triflupromazine-thiopentone anaesthesia. All animals were catheterized and allotted to 2 groups of 6 animals each. In group I urethral incision was not sutured while in group II urethra was sutured with 5-0 chromic catgut using swaged on needle over the indwelling urethral catheter in simple continuous pattern. The muscle and subcutaneous tissues were sutured in similar pattern. Skin edges were approximated with 1-0 braided silk. The animals were given a course of sulphadiazine (200 mg) and trimethoprime (400 mg), i.v. @ 15 mg/kg b.wt. every 12 h for 5 days and were observed for 21 days. Vital signs, urine analysis and haematological parameters were recorded on 0, 1, 2, 3, 14 and 21 days, postoperatively. On 21st day pelvic urethrostomy was performed in all animals and penis was dissected out to carryout positive contrast urethrography using lead oxide and soap solution to get morbid urethrographs. Urethral tissue at operated site was taken for histopathological study.