Efficacy of pimobendan in the treatment of congestive heart failure associated with Dilated Cardiomyopathy in dogs

摘要

Total 20 clinical cases of congestive heart failure (CHF) associated with dilated cardiomyopathy(DCM) were divided into two equal groups. Dogs of gr-I were treated orally with pimobendan 0.25mg/kg b.wt bid and gr-II with digoxin 0.22 mg/m~2 bid. In addition all the dogs orally received enalapril 0.5mg / kg b.wt once daily and furosemide 2mg/kg b.wt. b.wt bid and treatment was continued for 45 days. Therapeutic efficacy was determined by comparative assessment of M-mode left ventricular indices between dogs of two treatment groups. Combination of pimobendan, enlapril and furosemide was found to be effective in the treatment of CHF associated with DCM.