NA;During tumor imaging research, the authors incidentally discovered that Tchyphen;99m MIBI is taken up by pulmonary sarcoidosis. In order to evaluate this uptake, they performed Tchyphen;99m MIBI planar and SPECT imaging in 7 patients and compared it with Gahyphen;67. Six out of 7 patients showed evident uptake of Tchyphen;99m MIBI in enlarged hilar lymph nodes. One of the patients, who had been on corticosteroid treatment, showed only faint uptake lpar;negative resultrpar;, in whom Gahyphen;67 uptake was seen in hilar lymph nodes although it was less evident than the uptake in the other patients. The lymph nodes were better demonstrated with Tchyphen;99m MIBI. The fact that enlarged hilar lymph nodes in a patient on corticosteroid treatment showed faint uptake suggests that Tchyphen;99m MIBI could be helpful for assessing the response to treatment. The preliminary experience in a limited number of patients showed that Tchyphen;99m MIBI is taken up by pulmonary sarcoidosis and it appears to be a potential alternative to Gahyphen;67. Further study is necessary to evaluate its ultimate role in pulmonary sarcoidosis imaging.
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