SYNTHESIS OF 1,3,5-TRI-p-[(2-ARYL-3H-QUlNAZOLIN-4-ONE-3-YL)-PHENYL]-2,4,6-HEXAHYDRO-1,3,5-s-TRIAZINES AS POTENTIAL ANTITMV AND ANTIBACTERIAL AGENTS

摘要

2-Aryl-3-(4-aminophenyl)-3H-quinazoline-4-ones 2 were treated with formalin in excess in abs ethanol to furnish 1,,3,5-tri-p-[(2-aryl-3H-quinazolin-4-one-3-yl)phenyl]-2,4,6-hexahydro-1,3,5-s-triazines 3.The s-triazines 3 have been screened fortheir antiviral activity against Tobacco mosaic virus(TMV)from the host Nicotiana tabacum CV samsun'NN'and antibacterial activity against five strains of bacteria.