SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 2-{4'-[(5'-ARYL)-4'-5'-DIHYDRO-1-PHENYL PYRAZOL-3'-YL]-PHENYL AMINO}-6-[BIS (2''-CHLORO ETHYL) AMINO]-4- METHOXY-1,3,5-TRIAZINES

摘要

A new series of phenyl pyrazolyltriazines has been prepared and screened for their antimicrobial activity. Triazines and pyrazoles exhibit antiinflammatory, anticonvulsant, antipyretic, antibacterial and antifungal activities. Prompted by these facts the synthesis of 2-{4'-[(5"-aryl)-[4"-5"-dihydro-1 "-phenyl pyrazole-3"-yl]-phenyl amino}-6-(bis (2"'-chloroethyl)-amino)]-4-methoxy-1,3,5-triazines (5a-5k) have been undertaken (Scheme-1).