Activated nitriles in heterocyclic synthesis: Synthesis of 6-thiophen-2-yl and 6-furan-2-ylthiazolo2,3—apyridine derivatives

摘要

A variety of new 6-thiophen-2-yl and 6-furan-2-ylthiazolo2,3—apyridine derivatives could be prepared via the reaction of 2-functionally substituted methyl-2-thiazolin-4-one with cyanomethylenethiophen-2-yl and cyanomethylenefuran-2-yl derivatives. The structure of the reaction products was established based on spectral dat