Loss of DNA following C-banding procedures

摘要

When metaphase chromosomes prelabeled with 3H-thymidine are treated with various C-banding procedures, autoradiographs show a significant amount of DNA loss in the euchromatic segments. The constitutive heterochromatin (C-positive areas) retain most of their label. G-band production following the trypsin procedure, however, does not indicate DNA loss.