Reassignment of MYCL1 to human chromosome 1p34.3 by fluorescence in situ hybridization

摘要

MYCLl has been previously mapped to lp32. This position was in contradiction with our mapping data of 1 p deletions in neuroblastoma cell lines. Using FISH on high resolution R-banded chromosomes with a YAC clone for MYCL1 we were able to reassign the gene to subband 1p34.3. This new map position is of importance for the establishment of an integrated map for chromosome 1 and the search for disease genes in this region.